Kinetics
USMLENutrition Prep
Master USMLE nutrition biochemistry through clinical reasoning — not recall. Built for the 2026 USMLE nutrition expansion across Step 1, Step 2 CK, and Step 3. Mapped to the JAMA 2024 nutrition-competency framework.
The Four-Pillar Loop
Every session runs
the same flow.
Question
Practice with NBME-format vignettes. Pick from five lettered choices. Get a mechanism-deep rationale for every answer — correct and distractor — plus a takeaway summary and JAMA competency tags.
Case
Open a patient vignette. Review the history. Order relevant labs at a cost — targeted workups earn more. Commit to a differential diagnosis.
Pathway
Once you nail the DDx, map the biochemistry. Drag substrate, enzyme, cofactor, and product into a mechanism chain that explains why the clinical picture emerged. Understanding builds as you build.
Spaced Repetition
Missed a pathway? It returns tomorrow. Nailed it? It advances to 3, 7, or 21 days. Wrong answers become entry points to mechanism mastery — every question links to a relevant pathway and case for drill-deeper learning.
Key Features
Question, case, pathway — one durable loop.
260+ NBME-Format Questions
Across Step 1, Step 2 CK, and Step 3. Five-option vignettes with full per-distractor rationales, clinical takeaways, and JAMA competency tags.
100+ Clinical Cases
Physician-reviewed vignettes covering deficiency, toxicity, and dysregulation. Order labs at a cost. Commit to a DDx. Every case ties back to a mechanism.
70+ Interactive Pathways
Drag substrates, enzymes, cofactors, and products. Build the biochemistry chain that explains the clinical picture. Clinical pearls at every step.
Competency Dashboard
Track your progress against every JAMA 2024 nutrition competency the app teaches. See where you're strong, where to drill deeper.
Spaced Repetition
3-day, 7-day, 21-day intervals built directly into the study loop.
Drug-Nutrient Index
Causal chains, not lists. Searchable index for fast lookup at the bedside or before exams.
JAMA 2024 Alignment
Every case, pathway, and question mapped to the framework the USMLE cites as its alignment standard.
Content
22 topic anchors. Everything the 2026 USMLE tests.
13 vitamins, 6 minerals, and 3 macronutrient pathways — covered through the question → case → pathway loop.
13 Vitamins
A, D, E, K, C, B1 (thiamine), B2 (riboflavin), B3 (niacin), B5, B6, B7, B9 (folate), B12 (cobalamin)
6 Minerals
Iron, calcium, magnesium, zinc, iodine, selenium
Carbohydrate Metabolism
Glycolysis, gluconeogenesis, insulin signaling, glycogen, pentose phosphate
Fatty-Acid Metabolism
β-oxidation, ketogenesis, fatty-acid synthesis, NAFLD/SREBP, lipid transport
Amino-Acid Metabolism
Urea-cycle nitrogen disposal, hyperammonemia, transamination
Step 2 Macronutrient Emphasis
Refeeding syndrome, ketosis physiology, insulin resistance, protein-energy malnutrition
Drug-Induced Deficiencies
Taught as causal chains. Metformin/B12, phenytoin/folate, TMP-SMX/folate on PCP prophylaxis. Plus a searchable interaction index.
Lifespan-Specific Pathways
Periconception folate, maternal iodine, infant B12, neonatal vitamin K, congenital cretinism.
Eating Disorders & Refeeding
DSM-5 identification criteria with the refeeding-syndrome management protocol.
Food Allergy vs Intolerance
Cow's milk protein allergy, celiac disease. Plus nutrition label interpretation for chronic-disease counseling.
Why Kinetics
Built for the 2026 USMLE
nutrition expansion.
The 2026 update broadened nutrition biochemistry and chronic-disease testing across Step 1, Step 2 CK, and Step 3. Every Kinetics case, pathway, and question is mapped to the JAMA 2024 nutrition-competency framework that the USMLE cites as its alignment standard.
Who it's for
From M1 biochemistry through board recertification.
USMLE Step 1, Step 2 CK & Step 3
Medical students preparing for any Step exam in the 2026 cycle
M1 / M2 Medical Students
Biochemistry and nutrition coursework foundations
International Medical Graduates (IMGs)
US licensure preparation aligned to the 2026 update
Residents
Reviewing nutrition for in-training exams or board recertification
PA, NP & Pharmacy Students
Mastering nutrition mechanisms for boards and clinical practice
Simple Access. No Complications.
Free
Vitamin B12 unlocked forever
- 6 clinical cases (pernicious anaemia, nitrous-oxide SACD, infant of vegan mother, metformin in diabetics, post-bariatric SACD, terminal ileal Crohn)
- 4 pathways (MMA cycle, breastmilk-infant myelination, metformin–B12, PPI multi-nutrient malabsorption)
- 17 NBME-format questions
- Complete question → case → pathway → review loop
Full Unlock
One-time purchase · no subscriptions
- All 22 topic anchors
- All 260+ NBME-format questions
- All 100+ clinical cases
- All 70+ biochemistry pathways
- Competency dashboard
- Every future content update
Built by Diagnostic Studios — also makers of
MedDiagnosis — clinical case simulator. PathoPlay — disease and drug mechanisms.
MedDiagnosis FAQ
Frequently Asked Questions
Yes. Vitamin B12 is unlocked forever — 6 clinical cases (pernicious anaemia, nitrous-oxide SACD, infant of vegan mother, metformin in long-term diabetics, post-bariatric SACD, terminal ileal Crohn resection), 4 pathways (MMA cycle, breastmilk-infant myelination, metformin–B12 mechanism, PPI multi-nutrient malabsorption), and 17 questions. Enough to run the full question → case → pathway → review loop and decide if Kinetics fits your study style.
One-time purchase, no subscriptions. All 22 topic anchors, 260+ NBME-format questions, 100+ clinical cases, 70+ biochemistry pathways, spaced-repetition queue, competency dashboard, and every future content update.
Yes. Every case, pathway, and question is mapped to the JAMA 2024 nutrition-competency framework — the alignment standard the USMLE cites for its 2026 nutrition expansion across Step 1, Step 2 CK, and Step 3.
NBME-format vignettes with five lettered choices (A–E). Every option — correct and distractor — gets a mechanism-deep rationale, a takeaway summary, and JAMA competency tags. Wrong answers become entry points to a relevant pathway and case, not dead ends.
Yes. 70+ interactive mechanism-chain pathways across 13 vitamins, 6 minerals, and 3 macronutrient pathways — carbohydrate, fatty-acid, and amino-acid metabolism (including urea-cycle nitrogen disposal). Clinical pearls at each step.
Taught as causal chains, not lists: metformin and B12 in long-term diabetics, phenytoin and folate in seizure patients, TMP-SMX and folate on PCP prophylaxis, and more. Includes a searchable drug-nutrient interaction index for fast lookup.
Every session runs a full loop: NBME-format question → patient case → biochemistry pathway → spaced-repetition review. You're not recalling facts — you're reasoning through them and building durable understanding.
Yes, fully offline once downloaded. No internet required.
Yes. Kinetics is available on both the App Store and Google Play.
USMLE Step 1, Step 2 CK, and Step 3 students; M1/M2 medical students in biochemistry and nutrition courses; IMGs preparing for US licensure; residents reviewing for in-training exams or board recertification; and PA, NP, and pharmacy students mastering nutrition mechanisms.
Ready to master
USMLE nutrition?
Free tier includes Vitamin B12 forever. No credit card to start.
For educational use only. Not intended for clinical decision-making or patient care. USMLE® is a registered trademark of the FSMB and NBME. Kinetics is independent and not affiliated with or endorsed by the USMLE program, FSMB, or NBME.